In order to reduce the adverse impact on the operation of ETC in Henan province caused by the problems such as blocked ETC lane and disputed data caused by adjacent lane interference, Henan Provincial Department of Transportation proposed the adjacent road interference research project of ETC key equipment of Henan expressway. Through the research and analysis of the technical situation of ETC key equipment, combined with the test results of laboratory and simulation field platform, the technical solution for ETC key equipment in Henan province were proposed to reduce the occurrence of adjacent lane interference.